The United States Army attempts to isolate the city and area around Arnette, Texas, going as far as to take civilians into custody. Meanwhile, Hap, Vic, and Joe Bob have all begun coughing...

The army rounds up everyone who came into contact with Campion after he and his family escaped from the facility where the virus was being developed. This includes Stuart Redman, who was working at the gas station where Campion met his demise, and Stuart's wife.

Larry Underwood is a young, narcissistic pop singer who has just released his debut single "Baby, Can You Dig Your Man?" He runs up a lot of debt while living in Los Angeles and travels to New York to hide out, on the pretense of visiting his loving, but deeply disapproving mother.

Stuart Redman is forcibly held in a specialized center in Vermont, but proves immune to the virus. Harold is in love with Francis and tries to impress her with a self-written and published poem.

While Frannie and her father have a heart-to-heart talk, Stu Redman is getting tired of being kept in quarantine without any information and demands to talk to someone who can explain what's going on.

Shortly after the start of the epidemic, deaf-mute Nick Andros is beaten by some local thugs while walking on the street at night. He is mildly injured in the assault, and has dreams of Mother Abigail telling him to come see her in Nebraska.

Nick Andros wakes up in prison after a local doctor finds him on the street, nearly running him over. Nick manages to make himself understood and tell the sheriff who beat him.

Stu Redman is becoming increasingly impatient in quarantine and plays a mean trick on Dietz, who comes to discuss his situation.

Public officials continue to deny that there is an epidemic, but Larry's friend in L.A. is very concerned about what is happening there. Meanwhile, Poke and Lloyd attempt to rob a store.

When reporters who are trying to reveal the truth become victims of a brutal attack, it becomes clear how far the government will go to keep the deadly influenza a secret.

Down at the jail, Nick is trying to take care of the guys who are locked up, even though they are mocking him cruelly. The doctor shows up, gives him some bad news, and makes a suggestion that Nick finds surprising.

As the situation in New York becomes increasingly chaotic, Larry goes to his mother's house to find her extremely ill.

As the situation worsens, officials at the CDC repent and Nick is forced to kill in self-defense.

While Frannie tries to take care of her ailing father, they listen to people call into a local radio show to talk about the virus. However, exposing the truth has terrible consequences for the host of the show, Rae Flowers.

Stu has an encounter with Mother Abagail in which she tells him that he is in danger and needs to escape the CDC in Vermont. Meanwhile, it seems that the Dark Man is not just an imagined threat.